RAGE anticorps

N° du produit ABIN285943

Cet anticorps Chèvre Polyclonal détecte spécifiquement RAGE dans WB, IHC et ELISA. Il présente une réactivité envers Mammifères.

Aperçu rapide pour RAGE anticorps (ABIN285943)

Antigène: RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))

Reactivité: Mammifères

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp RAGE est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-RAGE anticorps

Specificité: Specific for Amino acid sequence 385-399 of human receptor for advanced glycated end products.0.1% NaN3

Immunogène: RAGE antibody was raised in goat using a peptide, PKKPPQRLEWKLNTGRTE, as the immunogen.

Information d'application

Indications d'application: ELISA: >1:260,676, IHC-P: >1:400, WB: >1:3,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as liquid whole serum without preservative

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Détails sur RAGE

Antigène: RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))

Autre désignation: RAGE

Sujet: The Receptor for Advanced Glycosylated End Products (RAGE) is a member of the immunoglobulin superfamily of cell surface molecules that binds molecules that have been irreversibly modified by non-enzymatic glycation and oxidation, and are know as advanced glycation end products (AGEs). It is expressed by endothelium, mononuclear phagocytes, neurons and smooth muscle cells. Whereas RAGE is present at high levels during development, especially in the central nervous system, its levels decline during maturity.

Pathways: Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteins